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Zhi Shi Li Zhong Tang 枳實理中湯(集)
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- ACM/CCM/TCM Global Status: Safe & Effective
Let Your Inner Glow Overflow™
Zhi Shi Li Zhong Tang Concentrated Decoction™ is Si Jin Bao’s proprietary formula designed to warm and rectify the Middle Jiao, expel Cold, and move Qi stagnation in the digestive and abdominal channels. Building on the classical Li Zhong Tang framework, this formula adds Zhi Shi (Immature Bitter Orange) to break accumulation and descend rebellious Qi, while Gan Jiang and Ren Shen restore Yang and replenish the original Qi of the Spleen and Stomach. It is indicated for patterns of Cold accumulation in the Middle Jiao with concurrent Qi stagnation — particularly where digestive weakness, abdominal fullness, and cold extremities present together.
A Cold, Stalled Middle — Warmed and Set Moving
Zhi Shi Li Zhong Tang is Si Jin Bao’s proprietary extension of the classical Li Zhong Tang — built to warm and rectify the Middle Jiao, expel Cold, and move the Qi that has stalled in the digestive center.
When the Middle Jiao turns cold and weak, digestion slows, food and Qi stop moving, and the body’s warmth no longer reaches the limbs. This formula restores the Spleen and Stomach’s warming, transforming function — and adds Zhi Shi to break the accumulation and send rebellious Qi downward. A cold, stalled middle is both warmed and set moving again.
Built on Li Zhong Tang
Li Zhong Tang — the “Regulate the Middle Decoction” — is one of the foundational warming formulas of the classical canon, recorded in Zhang Zhongjing’s Shāng Hán Lùn for Cold from deficiency of the Middle Jiao. Its four herbs — Ren Shen, Gan Jiang, Bai Zhu, and Zhi Gan Cao — warm the center and rebuild Spleen and Stomach Qi.
This proprietary formula builds on that frame. It adds Zhi Fu Zi to deepen the Yang-restoring, Cold-dispelling action — the move that classically defines Fu Zi Li Zhong Tang — and Zhi Shi to break accumulation and descend rebellious Qi. The result extends the classical formula to patterns where Cold deficiency and Qi stagnation present together.
The Middle Jiao — the Spleen and Stomach — is the body’s center of transformation, where food becomes Qi and Blood. When it runs cold and weak, everything downstream slows: appetite fades, the abdomen fills, the stool loosens, and warmth fails to reach the hands and feet. Warm and rebuild the center, and the rest follows.
Cold in the Middle Jiao with Qi Stagnation · 中焦虛寒氣滯
The pattern this formula answers is Cold from deficiency of the Middle Jiao with concurrent Qi stagnation — digestive weakness, abdominal fullness, and cold extremities presenting together. The center is too cold to transform food and too stalled to move it, and the cold reaches outward to the limbs.
- Abdominal pain & cramping; bloating & distension
- Epigastric fullness; chest oppression
- Poor appetite; nausea & vomiting; hiccups; acid reflux
- Loose stools; cold-type diarrhea; irritable bowel
- Cold extremities
- Fatigue & low energy; weakness & pallor
Six Herbs: Warm, Tonify, Move
Gān Jiāng and Zhì Fù Zǐ carry the warming work. Gan Jiang warms the Middle Jiao and expels Cold at the formula’s center; Zhi Fu Zi restores Yang and drives Cold from the interior, reaching the cold extremities the center can no longer warm.
Rén Shēn, Bái Zhú, and Zhì Gān Cǎo rebuild — the classical Li Zhong core. They tonify Spleen and Stomach Qi and replenish the original Qi, while Bai Zhu dries the Damp that pools in a cold, weak middle and Zhi Gan Cao harmonizes the whole.
Zhǐ Shí moves. It breaks the accumulation and descends rebellious Qi — resolving the fullness, distension, and counterflow (reflux, hiccups, nausea) that warming and tonifying alone would leave behind. Warm the cold, rebuild the weak, move the stalled.
When to Reach for It
Reach for Zhi Shi Li Zhong Tang when digestion is cold, weak, and stalled — the patient who is chilled and tired, bloated after eating, with poor appetite and loose stools, whose hands and feet stay cold. It suits chronic, functional digestive complaints that trace to a cold, deficient center rather than to heat or excess.
Western conditions and terminology that are commonly associated with these TCM patterns:
- Irritable bowel syndrome, functional dyspepsia, chronic gastritis, colitis
- Gastroparesis, SIBO, malabsorption, post-surgical digestive weakness
- Hypothyroidism, adrenal insufficiency, chronic fatigue
- Raynaud’s phenomenon, hypotension
Built on the classical Li Zhong Tang frame, this formula brings together six herbs that warm the cold Middle Jiao, rebuild Spleen and Stomach Qi, and move what has stalled. The cards below detail the nature, flavor, channels, and actions of each — drawn from the classical materia medica — along with how each functions within this specific formula.
Two herbs warm the cold center; three rebuild the Spleen and Stomach Qi that the cold has weakened; and one breaks the accumulation and sends the rebellious Qi down. Built on the classical Li Zhong frame and extended with Zhi Fu Zi and Zhi Shi, the six work as a single instruction — warm what is cold, rebuild what is weak, and move what has stalled.
Si Jin Bao Concentrated Decoctions™ are activated in hot water, steeped briefly, and taken warm. Follow the four steps below, then refer to the age-appropriate dosing grid.
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Step 01ShakeShake the bottle well before each use.
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Step 02Add Hot WaterAdd the age-appropriate dosage into 1 oz of hot water, as you would for tea.
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Step 03SteepCover and steep for 5 minutes, then allow to cool to a warm, drinkable temperature.
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Step 04DrinkDrink warm, twice daily or as directed by your practitioner.
What follows is the peer-reviewed evidence on the six herbs that compose this formula — each selected for a documented role in warming the Middle Jiao, rebuilding Spleen and Stomach Qi, reviving Yang, or restoring digestive motility.
No herb here was published under the name Zhi Shi Li Zhong Tang — it is a proprietary composition built on a classical frame. But each of its six members has been examined on its own terms, and the findings converge on what the classics described: a cold, weak, stalled middle restored by warming, rebuilding, and moving. The studies name the mechanisms — anti-fatigue and Qi-restoring, spleen-regulating and anti-inflammatory, warming and anti-nausea, Yang-reviving and cardiotonic, gut-protective, and prokinetic. The instruction underneath has not changed: warm what is cold, rebuild what is weak, and set the middle moving again.








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